I agree that turnover battle is #1, but the run game is #2. If Abdullah gets going and busts some big ones then MSU will have to play a lot less aggressive in defending the option and that opens things up a lot for TA. If MSU's run game gets going then Nebraska's D is going to be battling uphill on TOP which is how we typically like to dictate games.
Has MSU faced any option this season? I've watched some MSU games and haven't seen a single option play run against their defense. Since option is a classic counter to blitzes, I'm excited to see if NU challenges the blitz with speed and lead options. Ameer could really hurt them on the edges with some good option calls. Also throwing to Ameer in the flats may be effective. Denicos Allen has the speed to get outside with Ameer, but Bullough and the other LB (forgot his name) don't look to have the lateral quickness.
Allen is the best defender for MSU, IMO. That guy tackles well, takes on blockers, and has good speed. Hopefully NU can get into the right play calls to take advantage when Allen blitzes.