Nucleotide entropy was introduced into the spanning tree of genetic distance from Omicron to other variants of SARS-CoV-2. When we weight average genetic distance at each marker by the relative entropy, we derive a 2.8 year genetic distance between Delta & Omicron.

January 2018 pic.twitter.com/coedLVjj81

— Ethical Skeptic ☀ (@EthicalSkeptic) December 9, 2021