I'm going to the USC game by myself (shameless plug: other ticket for friend that couldn't make it for sale in the classifieds).
But this summer I worked for 2 months in a strange town by myself, and although I was socialable at work and such, after work I'd go out and I met some new people... so it shouldn't be too bad.
Abd since we all have the same passion for the game and the 'Skers, you'll hardly notice that you're by yourself-- quite the opposite you'll be surounded by 85,000 other fans too.