You don't become perfect by chance you do it by honing in and beating your craft over and over and over. It is constantly working hard at something repeatedly. Running formations under center to me, sounds like we're throwing stuff at a wall hoping it'll stick. We may run the ball more than we pass but, it isn't very effective. I continue to ask myself, "Are we a smash mouth team or an Air Raid? Multiple? What?" I think that the more they continue not to find their identity, the more we'll struggle on offense.
The thing about a specific play on offense, is that it can be broken down into 'concepts'. Rather, a set of common movements that cause a play to work.
You can see this in passing plays quite easily. The 'Texas' concept involves a pair of mesh routes (usually with a rub or a pick) at the linebacker level, coupled with a sort of wheel route by the FB or HB, but over the center of the field, rather than down the sideline. You can run that play out of damn near any formation with damn near any personal group. If you have a shotgun 4-wide look, have the slot recievers run the mesh and the HB run the Texas route. Or, in a 2-TE I-formation, have the two TE run the mesh, etc.
The same holds true for run blocking schemes. A run play called 'inside zone's uses zone blocking to (hopefully) open up several holes along the defensive line using double teams at the points of attack, and usually one or more linemen will climb up the field to block a LB as well. The RB simply chooses the most open lane and runs for it.
A Trap run play has the center leave the nose guard unblocked, and instead crashes down either towards another D-lineman, or climb up to a LB, while a guard pulls around and blindsides the nose guard from the side where he doesnt expect it and knocks him out of the way of the ball carrier. That leaves 4 or 5 yards of almost always clear ground for the ball carrier to gain straight up the middle of the field. You can run that play out of nearly any formation, but it works best in a formation where the RB or FB can hit the line of scrimmage very quickly, so that the defense can't react in time.
A clever coach can find a way to run nearly any concept out of nearly any formation. If the 'core concepts' of a coach's offensive system dont change from formation to formation (and are only adjusted to account for the new offensive alignment, and of course adjusted for defensive alignment) then the formation matters very little. Of course, quick-hitting plays like FB Dive or a Trap run work best with a QB under center and a RB closer to the line of scrimmage than is typical for a Shotgun or Pistol look, but that doesnt mean it can't be done.
Blocking schemes (like pulling linemen) and running routes (like counters) or pass routes (like a curl, an out route, or a fade) in specific combinations are concepts. The best coaches run advantageous concepts out of unusual formations to catch defenses by surprise. If the core concepts you run dont change, it doesnt really matter how many formations your offense lines up in; they already know what to do.
And that, my friend, is 'being multiple' done right.