I think you will see the option (the Osborne versions) and the wishbone make a serious come. Hell, all the Wildcat is, is the old single wing shotgun offense with a few tweaks here and there.
I don't, for a lot of reasons.
1) The passing game is simply more efficient from a per play standpoint.
2) The rules heavily favor the passing game.
3) The size of today's athletes favors the passing game.
4) Very, very few current coaches are trained in sequential playcalling.
None of those say that the option can't work. None of those say that the option won't work. None of those say the option cannot be part of an overall offensive system.
They simply say we will not see a large scale trend towards option/wishbone/veer offenses in the near future, imo. The forward pass has simply become a dominant figure in modern football and as the coaches that started in a sequence based offense continue to retire, that will only become more the case. I'm not saying the option is going to leave the game, but the multiple wide receiver offenses have replaced it as the defacto choice amongst the lesser talented institutions and that was always a huge draw for the option. The option's future I believe will exist as a complementary part of an existing offense.
What we're seeing is versatility come to the forefront, even in the slow to change NFL: 40 Nickel, 33, 3-4......all of these structures have become popular because they bring more flexibility in personnel.
One of the things I have a hard time explaining to people is the rise of the 3-4 in the NFL. The standard idea amongst the public is the 3-4 is a 2 gap scheme, with a 0 tech NT, and with little variance from that singular idea. It is so much more flexible than that. The same thing happens at the college level, but instead of flexing the DE/OLB we're flexing a LB/S/CB. Teams have different ways of doing it, but at the end of the day it is in response to offensive variability. Defenses need to be more versatile in their base sets. Gone are the days we put 8 in the box expecting a lead ISO on first down and only moving to a Nickel on 3rd and Intermediate or longer. It may be 5 wide now on first down and 2 back on second down! Most defenses these days run a lot of fronts, to the point even calling an NFL defense a 3-4 is a bit of a misnomer. Some "3-4" teams aren't lined up in a "3-4" by alignment more than 10-15% of the time.
You really can't discuss modern football defenses without looking at them by personnel and by alignment. We just play so many fronts these days that thinking about the defense as a whole as a combination just won't work.
It's not your daddy's game anymore, on either level. As these defenses become more versatile, the offenses again respond. The basic passing concepts used in most multiple receiver offenses are zone based; attempting to outnumber zonal defenders in a single part of the field. Defenses have adjusted by using more man and matchup zone philosophies. More film study is done now that helps players recognize offenses by passing concept rather than by route. More understanding on the defensive side is happening in regards to tendencies and route combinations. Bill Callahan may have failed in a lot of areas as a head coach, but he deserves a great deal of credit in upgrading our technology in these regards. When you see Asante and Amukamura change the defense at the line so seamlessly, that's a direct consequence of their detailed film study. No defensive structure is more powerful than the ability to recognize the offense's intentions, just as no offensive structure is more powerful than the ability to defeat the defense's on the fly.
The response to the other team playing man is to either attempt to outnumber them in the box, with schemes like the zone read or to create open space by bringing players closer to the line with bunch formations, or utilizing more tight ends. The option is another way; teams that play a lot of man defense are more susceptible to being blocked by receivers. Bubble screens.........the list goes on and on.
What we're seeing are offenses doing a little bit of all of this. They're not as specialized as they were, which you'll no doubt notice bothers many traditional college football fans who relate their team by an easily recognizable structure. I applaud Watson in that he understands this need for versatility. I was really against his hire, and made my opinion on that known publicly, but in 2008 I issued a public apology......that offense married these things together and became difficult to defend. If we keep an open mind, and improve from a technical aspect, I think we'll see this variability again. Watson is the type of coach that is willing to step out of his comfort zone a bit and bring together divergent ideas, and that's the type of offense I think we'll see in the next decade. I think we'll see teams attack versatility with versatility.