From a Hokie perspective ...
I have a hard time rooting for some of our ACC rivals even in non-conference games. I love to see UVA lose. Even though their losses to W&M and TCU may have hurt the conference, it's just too entertaining to watch their fans squirm.
I have a pretty strong dislike for Boston College, too. So I'll begrudgingly root for them in non-conference games. Same with Miami. However, I've mellowed in my dislike for Miami the last few years since they've been struggling, and I have found it easier to root for them in out-of-conference games.
Everyone else in the ACC I have no problem rooting for them in non-conference games and when it helps Tech.
Sounds like Husker fans view on Colorado.
Good luck to your Hokies on Saturday.